Acesulfame potassium is an artificial sweetener used throughout the world in food and beverages. doi: 10.1289/ehp.114-a516a. Male and female Tg.AC hemizygous and p53 haploinsufficient mice were exposed to acesulfame potassium (at least 99% pure) in feed for 9 months. ABSTRACT. Two tested rats showed that there could be some chances for the food additive to cause cancer. Epub 2013 Apr 19. In summary, studies in test tubes and lab animals suggest that acesulfame potassium does not cause cancer. In fact, because of the … Integr Environ Assess Manag. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Acesulfame potassium has been thoroughly tested in several long-term animal studies. Environ Health Perspect. The studies were aimed towards determining any kind of threat the sweetener may pose to human health. Please enable it to take advantage of the complete set of features! Get the latest research from NIH: https://www.nih.gov/coronavirus. It is known by it’s manufacturing names Sunett and Sweet One. H. 3. This site needs JavaScript to work properly. Get the latest public health information from CDC: https://www.coronavirus.gov. According to the CSPI, acesulfame potassium may possess carcinogenic properties. J Mol Neurosci. H. 4. Male and female Tg.AC hemizygous and p53 haploinsufficient mice were exposed to acesulfame potassium While there isn’t much evidence that acesulfame potassium leads to cancer or allergies, some side effects are still possible. 7789-38-0) in genetically modified (FVB Tg.AC Hemizygous) mice (dermal and drinking water studies) and carcinogenicity studies of sodium bromate in genetically modified [B6.129-Trp53tm1Brd (N5) haploinsufficient] mice (drinking water studies). Dangers of Acesulfame Potassium (Ace-K) One of the major issues surrounding Ace-K is that it contains the carcinogen methylene chloride. Acesulfame potassium is an artificial sweetener used throughout the world in food and beverages. Under the conditions of this 9-month feed study, there was no evidence of carcinogenic activity of acesulfame potassium in male or female p53 haploinsufficient mice exposed to 0.3%, 1%, or 3%. Environ Health Perspect. Sweet preference modified by early experience in mice and the related molecular modulations on the peripheral pathway. We tested if acesulfame potassium could cause cancer in two different strains of genetically modified mice. A Review of the Environmental Fate and Effects of Acesulfame-Potassium. 9-MONTH STUDY IN p53 HAPLOINSUFFICIENT MICE: Groups of 15 male and 15 female p53 haploinsufficient mice were fed diets containing 0%, 0.3%, 1%, or 3% acesulfame potassium (equivalent to average daily doses of approximately 475, 1,500, or 4,700 mg/kg to males and 570, 1,800, or 5,700 mg/kg to females) for 40 weeks. USA.gov. Neuroendocrine and Metabolic Effects of Low-Calorie and Non-Calorie Sweeteners. According to studies, headaches, depression, nausea, mental confusion, liver effects, kidney effects, visual disturbances, and cancer can all result from long-term exposure to methylene chloride. 5 . 4. Acesulfame potassium (acesulfame-K) is a potassium salt that is about 200 times sweeter than sucrose. Acesulfame potassium was nominated by The Center for Science in the Public Interest because of its widespread use. NIH It is an all-purpose sweetener that is used in baked goods, candies, chewing gum, desserts, diet drinks, gelatins, puddings and as a tabletop sweetener in Sweet One and Swiss Sweet. Science Ace K is a salt made from potassium that contains methylene chloride. S Molecular Weight: 201.25 . Acesulfame potassium or ace-K (Sweet One, Swiss Sweet, Sunett). It is a good decision to be fully aware of potential dangers that may be associated with acesulfame potassium and many other variants of artificial sweeteners. Acesulfame potassium did not increase the frequency of micronucleated erythrocytes in peripheral blood of male or female Tg.AC hemizygous mice administered 0.3% to 3% in dosed feed. ACESULFAME POTASSIUM . KNO. Moriconi E, Feraco A, Marzolla V, Infante M, Lombardo M, Fabbri A, Caprio M. Front Endocrinol (Lausanne). Acesulfame potassium is an artificial sweetener widely used in beverages and foods. Genetic toxicology studies were conducted in mouse peripheral blood erythrocytes. 75-27-4) in genetically modified (FVB Tg.AC Hemizygous) mice (dermal, drinking water, and gavage studies) and carcinogenicity studies of bromodichloromethane in genetically modified [B6.129-Trp53(tm1Brd) (N5) haploinsufficient] mice (drinking water and gavage studies).

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