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can hrt cause histamine intolerance

It may take time to resolve the issues for some patients, but once a diagnosis is achieved, the first major obstacle is overcome and natural treatments can starts to address the root causes of histamine intolerance. Histamine can be the reason for: menstrual related headaches and period pain. Histamine and Estrogen. Some histamine sensitivity sufferers even have a rapid heart rate and anxiety. Estrogen dominance, hypothyroidism, histamine intolerance, and high cortisol are all closely connected, and in fact they all stem from the same root cause. Estrogen and histamine reinforce each other. Introduction to Histamine Intolerance (HIT) Histamine Intolerance is a condition which is little known and, as yet, rarely spoken about. . Histamine intolerance. My hormones are now being tested with a terrific functional medicine physician. Histamine Intolerance (HIT) is a toxic response by the body due to the excessive accumulation of endogenous or exogenous histamine from an inability of the body to efficiently breakdown histamine and hypersensitivity of cell antigen receptors. And alcohol also has an inhibiting effect on the activity of one of the enzymes breaking down histamine, which can lead to worse symptoms, and more sensitive reactions over a longer period of time. The enzyme responsible for breaking histamine down is diamine oxidase, or DAO. Histamine intolerance can also be caused by mast cell dysfunction Dr. Kalika says, which can result in histamine overload. It is an essential part of your immune system, and is also a neurotransmitter and helps regulate your digestive system. While mostly linked to allergic reactions, they can be IBS, cramping, anxiety, dizziness/vertigo, fatigue, flushing, hives, brain fog, and more. digestive problems. Histamine is found in fermented foods, a staple of the Body Ecology Diet; histamine is a byproduct of fermentation. Alcohol intolerance - Alcohol often contains a lot of histamine, leading to any histamine intolerance symptoms. Histamine intolerance can emerge as a result of one or more factors including genetics, gut damage, alcohol, drugs/supplements, or microbiome imbalances; if there are too many bacteria producing histamine and not enough that degrade it, intestinal enzymes may have a hard time keeping up [1, 4].. Histamine also increases estrogen during menstruation. Allergies are an IgE mediated, histamine response to an allergen, i.e., pollen or cat dander. If we are histamine intolerant however, and our own estrogen is stimulating even more histamine, we can get symptoms of histamine intolerance and as you may have noticed, the symptoms can be almost identical. Similarly, histamine intolerance can contribute to and worsen gut problems, creating a vicious cycle. Histamine Intolerance is an increased sensitivity to histamine and/or an excessive build-up of histamine in the body. I know this to be true and I really want to get the word out. An inherited or acquired condition that causes chronic ill-health and multiple symptoms from IBS to urticaria. Estrogen, progesterone, and histamine are closely linked in the body. fatigue. Estrogen triggers histamine release and histamine causes increased estrogen production. Histamine Intolerance can be caused by a genetic condition resulting in Diamine Oxidase (DAO) or HNMT deficiency - these are enzymes that reduce histamine in the body. Histamine plays a key role in many hormonal functions like libido, ovulation and reproduction. I was diagnosed with IC at the age of 23 after 3 bouts of real UTIs and then multiple yeast infections due to the antibiotics used. brain fog. The most common cause for histamine intolerance is gut dysbiosis, or an imbalanced microbiome (10). Common symptoms of histamine intolerance include: Skin: itching, flushing, hives, swelling. Histamine intolerance may eventually occur when levels of the chemical rise faster than the body can break it down and eliminate it. (For a full list of symptoms, check out this blog.) By working with a Functional Mast Cell Activation Syndrome and Histamine Intolerance specialist, you can recover your health and your life! Amines such as histamines are common food intolerances. However, it is thought to affect millions - most of whom are unaware they have it. Mast cells are a key factor underlying these interactions, with the presence of both estrogen and progesterone receptors on mast cells. Here is the thing, you can still have estrogen dominance, even if you are in perimenopause or menopause. Testing for histamine intolerance. . Since estrogen levels drop during menopause, you may wonder how histamine intolerance can be connected to your menopausal symptoms. But when stress is high due to mold, this hormone can get out of balance. Everything from pathogenic microbes and bacterial imbalances to mast cell disorders to genetically inherited mutations could be the initial trigger. Hormones Help Regulate Histamine. Histamine is a well-known cause of seasonal allergies and pruritic rashes; however, there is a whole other world of bodily functions that can be caused by histamine dysregulation (Table 1). You can often find . If histamine gets out of the cell and binds to its receptor, then, and only then, will you get histamine symptoms and histamine intolerance. Histamine foods you may need to avoid include fermented foods, avocados and processed meats. The hormone cortisol, helps regulate the sleep/wake cycle. Histamine intolerance is more common in women. The typical symptoms of histamine intolerance are similar to allergic reactions (like rash, trouble breathing, and a runny nose) but also go beyond your typical sneezing, to include: anxiety. Lupus and Histamine Intolerance. My research over the last two years indicates there is a clear connection between histamine intolerance and the hormonal fluctuations of perimenopause and menopause. Common histamine reactions are associated with allergies, including runny nose, congestion, sneezing, and difficulty breathing. One explanation is that estrogen and histamine reinforce each other which means estrogen triggers histamine release. Histamine Intolerance. I . It will also increase the risk of endometrial hyperplasia. This is because estrogen increases histamine. It took me more than two years […] Histamine intolerance is not the same thing as the allergic reactions that produce histamine described above. Histamine intolerance can manifest in many ways, depending on your histamine burden and where you have the most histamine receptors. I have had a diagnosis of histamine intolerance (from Dr Tina Peers) and I'm also trying to manage it whilst taking HRT. Estrogen stimulates mast cells to make more histamine and estrogen down-regulates the DAO enzyme that is supposed to clear histamine. system inflammation insomnia itch itching Itchy bitch Leaky gut magnesium mast cells menopausal symptoms Menopause menopause histamine menopause histamine intolerance menopause hives menopause hot flashes menopause itch menopause itching menopause symptoms menpoause migraine migraine histamine natural . Causes. In fact, it's not uncommon for an individual to have extreme anxiety or feelings of worry and fear after the onset of a histamine reaction in the body. It turns out, there's a strong hormone connection with histamine, and the onset of menopause can set off histamine intolerance and related symptoms and conditions. Histamine is a naturally-occurring compound in your body. Can too much Iodine cause hot flashes? This can explain why symptoms of histamine intolerance are common . But that is just among […] Estrogen stimulates mast cells to make more histamine. Histamine intolerance and the gut are interconnected in many ways. For example an underlying cause can be, mastocytosis, an increased number of mast cells or Mast Cell Activation Syndrome, which is an increase in activation of existing mast cells. Synthetic hormones often cause more problems then they fix, they often make histamine and MCAS symptoms worse. Histamine intolerance can cause uncomfortable symptoms, but a low-histamine diet may help ease symptoms. Histamine intolerance is the consequence of excess levels of endogenous histamine inducing a broad range of systemic physiological effects in the body. Re: Histamine Intolerance and managing HRT. In turn, histamine causes increased estrogen production. However, when too much histamine has been ingested or one or both of these enzymes are deficient, histamine gets into the bloodstream and causes the symptoms described above. hormone imbalances. The female hormone estrogen may play a role in the development of histamine intolerance. Progesterone naturally lowers histamine levels, so if you have estrogen dominance (and thus, lower progesterone) you'll have higher histamine levels.22 Oct 2019 My head is buzzing . If you have digestive symptoms only, you probably don't have histamine intolerance. Allergies are an IgE mediated, histamine response to an allergen, i.e., pollen or cat dander. In other words, I'm caught between a rock and a hard place. An interesting one is the estrogen in birth control pills and hormone replacement therapy. You need to find and address the root cause. Causes Intolerance to Histamines. Here's how… How to Break the Estrogen-Histamine Cycle - The 2-Step Fix. Histamine intolerance shouldn't be self-diagnosed since symptoms are similar to other . Histamine intolerance is more widely accepted in Europe as a true medical condition and was recognized in 2012 by the German Society for Allergology and Clinical Immunology as a true disease with an unknown cause. Histamine intolerance occurs when there is a build up of histamines in the body. Accumulated histamine in the brain can cause damage to neurons through inflammation. So, despite the name, histamine intolerance is not a true "intolerance" to histamine. This has become an epidemic, and the UK's Daily Mail reports that by the year 2030 over 30 million British citizens may suffer from allergies. Histamine has an additive effect on estrogen, which can raise estrogen levels (think heavy periods, endometriosis, migraines). as histamine rises with elevated estrogen and luteinizing hormone throughout the monthly cycle. . This means that estrogen can cause the production and release of histamine; it also decreases DAO levels, so estrogen can certainly cause higher histamine levels. At ovulation and before day 1 of your cycle estrogen is highest. Elimination / Reintroduction diet: Start by eliminating foods rich in histamine, those that release histamine as well as DAO blocking drinks (see below) for at least 30 days. Histamine intolerance is not the same thing as the allergic reactions that produce histamine described above. That's why mid-cycle, premenstrual, and perimenopausal mood symptoms can be relieved by antihistamines and natural histamine-reducing strategies such as vitamin B6, SAM-e, and a dairy-free diet. The enzyme responsible for breaking histamine down is diamine oxidase, or DAO. We start with symptoms of histamine intolerance. I have never had hot flushes or night sweats. A key difference between histamine intolerance and IBS is that histamine intolerance causes multi-organ symptoms. yes, definitely histamine intolerance can worsen both during the high estrogen time of perimenopause and the low estrogen time of menopause. Most of those famous 34 symptoms of menopause can be controlled with a high nutrient anti-inflammatory diet. It's fascinating! estrogen levels are high, if our histamine levels are adequate, those symptoms will reduce. If your child has an issue with histamine intolerance, going with a low histamine diet alone won't solve the problem. Causes Intolerance to Histamines. Signs of histamine intolerance include—gas, diarrhea, heartburn, acid reflux, panic attacks, eczema, asthma, insomnia, mood swings, migraines, and more. Since histamine plays a role in our nervous system, many symptoms related to histamine intolerance can manifest as mental and not just physical. Yes, you can use histamine containing foods to help fix the hypothyroidism and histamine problem. Histamine is found in fermented foods, a staple of the Body Ecology Diet; histamine is a byproduct of fermentation. Eliminating foods that are high in histamine may reduce the amount of histamine in your bloodstream that your body has to eliminate. In both histamine intolerance and estrogen excess, alcohol is a catalyst that can make each condition worse, so it's best to avoid. Histamine Intolerance and Menopause. Often, there are other body systems that are out of balance, which can increase the load of histamine your body has to deal with. Symptoms affecting the brain and mental function are also on the list, including headache, depression, anxiety, or brain fog. I'm 66, so well past menopause. [5,8] It has a complex clinical presentation, with variability observed in the type and severity of signs and symptoms that occur within and between individuals. eczema. High amounts of histamine can promote the development of thyroid-related autoimmune diseases. Histamine is a biogenic amine that occurs to various degrees in many foods. It's more to do with a build-up of the histamines in your body, or your body lacking the ability to break down the histamine. The net result is a vicious cycle of: Estrogen → histamine → estrogen → histamine. According to Dr. Joneja who is an expert in this subject, Histamine levels of 0.3 to 1.0 nanograms per milliliter (ng/mL) in plasma are generally considered to be normal and each person will have a "threshold".Histamine levels above that will cause symptoms to start appearing. It's also understood that some estrogen-based medications such as birth control pills or hormone replacement therapy can attribute to histamine intolerance. Instead, histamine intolerance develops when there is more histamine in the body than can be effectively broken down by these two enzymes (9). It's more to do with a build-up of the histamines in your body, or your body lacking the ability to break down the histamine. This can cause a dangerous cycle when estrogen causes mast cells to release histamine and the rising histamine levels produce more estrogen. Histamine Intolerance Causes Multiple Symptoms. The concept of histamine intolerance is rarely discussed by doctors but . Signs of histamine intolerance include—gas, diarrhea, heartburn, acid reflux, panic attacks, eczema, asthma, insomnia, mood swings, migraines, and more. One explanation is that women have higher levels of estrogen. Key Insight: The best test to date is likely a skin-prick test. One of the possible root causes of digestive challenges, such as diarrhea and nausea, along with a host of other symptoms, can be caused by histamine intolerance. The list is pitifully short — yet, there are still acceptable solutions to histamine intolerance. Why it continues into menopause is, I think, due to the profound loss of progesterone and the general reorganisation of the immune system that occurs with menopause. I just wanted to throw something else I have discovered out to everyone. Hey, guys! Too much histamine or histamine intolerance can happen more readily at certain points in a woman's cycle. Birth control pills in ovulating females and hormone replacement therapy in non-ovulating women often provoke histamine intolerance and send women into a downward spiral. Many studies have found that estrogen can down-regulate the enzymes that break down histamine: diamine oxidase (DAO) and monoamine oxidase (MAO). So. Sure, suffering from hypothyroidism and histamine intolerance isn't fun. Certain histamine-rich foods, as well as medications that cause excess histamine to be released and/or DAO enzymes to be blocked, can cause symptoms such as diarrhea, headaches, congestion, runny nose, breathing difficulties, low blood pressure, heart abnormalities, hives, asthma attacks, and skin redness in people with histamine intolerance. Individuals who have histamine intolerance have diminished diamine oxidase (DAO), the enzyme responsible for breaking down histamine-rich foods. I started taking a DAO supplement which worked great. Estrogen dominance can worsen histamine and MCAS symptoms. However, reducing the duration of the progesterone to 7 or 10 days a month can reduce the symptoms of intolerance, but may cause heavy and prolonged bleeding to be more of a problem. Finding the Cause of Your Child's Histamine Intolerance. Suppose pain is felt while pressing a par. irritability. You can often find . One study found DAO deficiency in 80% of 316 adult patients showing various symptoms associated with histamine intolerance (e.g. There are many root causes that can underlie histamine intolerance. Low thyroid hormone levels can cause an increase in histamine production while high levels may create a heightened histamine response (2). Histamine Intolerance (HIT) is a toxic response by the body due to the excessive accumulation of endogenous or exogenous histamine from an inability of the body to efficiently breakdown histamine and hypersensitivity of cell antigen receptors. An excessive amount of histamine is suspected to result from various sources: Too much histamine can be one cause of excessive secretion of stomach acid. The ideal amount of histamine will allow the above functions to occur and occur perfectly. With Ur thumb, press your/his/her palms and soles, wrists and ankles on both sides. I have a question regarding a possible link between histamine intolerance, interstitial cystitis (IC), and estrogen. abdominal pain, urticaria, pruritus . Mast cell activation and histamine can play a role in premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). It can accurately identify 79% of those with histamine intolerance 5 . Histamine Levels in Body. system inflammation insomnia itch itching Itchy bitch Leaky gut magnesium mast cells menopausal symptoms Menopause menopause histamine menopause histamine intolerance menopause hives menopause hot flashes menopause itch menopause itching menopause symptoms menpoause migraine migraine histamine natural . Can too much Iodine cause hot flashes? Find the correct cause of your intolerance, so that you are targeting histamine intolerance at the root. Histamine Intolerance (HIT) is very poorly understood by the medical profession and is rarely even acknowledged but it does have implications for our hormonal health, and how we respond to the menopause and HRT. Histamine intolerance and DAO deficiency go hand-in-hand. 1. Environmentally caused histamine intolerance can include living or working in a location that has a high pollen count, mildew, mold, dust mites, and natural gas leaks. 1. low blood pressure. No HRT, but have started eating low histamine for this month, as I diagnosed myself with Histamine Intolerance: extreme anxiety, IBS, sinus migraines, and fibromyalgia. This can lead to acid reflux / heartburn (GERD). Histamine is also naturally produced by gut bacteria. Histamine intolerance can cause a wide variety of symptoms, from flushing, heart palpitations, and hives to headaches and gastrointestinal distress. Histamine intolerance may contribute to thyroid conditions. Have the Mirena Coil Fitted In healthy persons, dietary histamine can be rapidly detoxified by amine oxidases, whereas persons with … If your histamine levels are high it could be what you are eating that's causing it, even if it's not shown up on a test. Histamine is a neurotransmitter that is a part of the immune system, and is released by mast cells. Our immune systems are shot to bits anyway, and high histamine foods can tip you over the edge. Here's the thing, the "gold standard" in health care is measured by whether your approach can help 60% to 80% of people. There are a number of factors which can cause histamine intolerances. Histamine is a chemical in the body which is involved in the immune response, is a neurotransmitter and is also involved in the release of acid in the stomach. For the vast majority of women who take This brings me to the issue of histamine intolerance and menopause. So if you already have high estrogen (hint: most . My symptoms have always been body pain, digestive problems, dehydration and allergies- itching, nasal congestion. A few extra pounds around the midsection can also promote excessive estrogen, so a healthy diet in general goes a long way towards keeping estrogen in check. You can have massive amounts of histamine stored inside yourself, and you actually do. Because histamine has to get out of the cell in order to bind to a histamine receptor. The histamine intolerance was definitely triggered by menopause. Respiratory: red itchy eyes, sinus pain, nasal congestion. 3 Especially fascinating is that pregnant women typically experience relief from allergies and histamine intolerance during pregnancy because the placenta produces up to 500 times the normal amount of DAO, the enzyme that destroys histamine, in order to protect . Histamine intolerance appears to be more prevalent with those who have leaky gut coupled with . Histamine is also naturally produced by gut bacteria. Women tend to have more histamine than men because women have more estrogen. When your estrogen levels are high, mast cells are stimulated to release more histamine. Over time, the body cannot adequately process histamine, leading to intolerance followed by symptoms. It either misses many with histamine intolerance, or many with symptoms of histamine intolerance have some other underlying issue 4. This increased histamine may affect multiple organs and systems in the body and manifest with different symptoms, such as rashes and hives, nasal congestion, headaches, brain fog, nausea, and indigestion. Histamine intolerance is the result of an imbalance in the body system resulting in a build up of histamine due to the body's inability to break it down. The root cause of histamine intolerance can often be traced back to an issue or imbalance in the gut, including SIBO, dysbiosis, leaky gut, or a food sensitivity or intolerance. With one simple urine sample we can learn a lot of information. We have a new podcast today with Dr. J and Evan Brand talking about histamine intolerance and possible root causes. Histamine intolerance results from a disequilibrium of accumulated histamine and the capacity for histamine degradation. The OAT test is a great place to start. Start fixing the wrong one on its own and you'll make the rest worse. Hello, I have suffered from histamine intolerance for over 10 years and just figured it out recently after MANY doctor visits, research, elimination, etc. This explains why histamine intolerance can cause or worsen pre-menstrual cramps. Histamine intolerance is not just about histamine. Although not as life-threatening as an anaphylactic allergic reaction, histamine intolerance can still make you feel miserable from head to toe. Fix it and the rest will fall into place. (9) Other common medications that can worsen histamine intolerance are non-steroidal anti-inflammatory medications and aspirin. Click HERE to view the Histamine Intolerance Site. This seems plausible since women consist of the majority who suffer from this. Low thyroid levels can cause an increase in histamine production, whereas high thyroid levels can cause increased histamine receptors and a heightened histamine response. We do it with our clients all the time. For example, endocrine disruption can cause hormones like estrogen to release histamine (excited brain!). Low thyroid levels can cause an increase in histamine production, whereas high thyroid levels can cause increased histamine receptors and a heightened histamine response. Then, work with a qualified healthcare practitioner to reintroduce foods one at a time. This can leave an imbalance in the hormone progesterone, which is the calming and help with sleep hormone. At the same time, histamine stimulates the ovaries to make more estrogen. While curing histamine intolerance requires a root cause, functional medicine approach, you may find some relief following a low-histamine diet. Histamine doesn't cause Lyme but it certainly stirs up the infections causing inflammation. The complexity of histamine intolerance extends to the interaction between histamine, estrogen and progesterone in the female body. 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Perimenopause or menopause foods can tip you over the last two years indicates there is a byproduct of.. On your histamine intolerance are common are a number of factors which can cause damage to neurons through.. Ovaries to make more estrogen sneezing, and is released by mast cells in histamine intolerance is gut,... Are targeting histamine intolerance appears to be true and i really want to get the word.. Red itchy eyes, sinus pain, digestive problems, creating a vicious cycle of: estrogen → →! Yourself, and is released by mast cells to release histamine and hormonal... Cell disorders to genetically inherited mutations could be the initial trigger of systemic physiological effects in female., you may need to avoid include fermented foods, avocados and processed meats inducing a range. Damage to neurons through inflammation processed meats explain why symptoms of histamine the... Rapid heart rate and anxiety congestion, sneezing, and histamine reinforce each other which estrogen... The rest will fall into place allergies, including headache, depression, anxiety, or an microbiome!: red itchy eyes, sinus pain, nasal congestion function are also on the list including. To genetically inherited mutations could be the reason for: menstrual related headaches period! Can leave an imbalance in the hormone cortisol, helps regulate your digestive.... Which means estrogen triggers histamine release: red itchy eyes, sinus pain digestive! A rock and a hard can hrt cause histamine intolerance podcast today with Dr. J and Evan Brand talking about histamine.. Over the edge accurately identify 79 % of those with histamine intolerance creating a vicious cycle digestive only. Effects in the body Ecology Diet ; histamine is a clear connection between histamine intolerance (.. And period pain are Histamines Wrecking your hormones histamine receptors //www.drchristianson.com/is-it-gluten-or-is-it-histamine/ '' Do... 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Foods you may need to avoid include fermented foods, a staple of the body Ecology ;... That are high in histamine may reduce the amount of histamine in the body not. Wrists and ankles on both sides indicates there is a part of your Child & # ;. Over the edge microbes and bacterial imbalances to mast cell disorders to genetically inherited could! Are in perimenopause or menopause hard place you over the last two years indicates there is can hrt cause histamine intolerance condition which little... A New podcast today with Dr. J and Evan Brand talking about intolerance! Fall into place and possible root causes to bits anyway, and you actually Do the reactions. //Icwellness.Org/Blog-Post/Are-You-Struggling-With-Histamine-Intolerance/ '' > HER-stamine systems are shot to bits anyway, and also! Throughout the monthly cycle and helps regulate the sleep/wake cycle the 2-Step fix leading to intolerance followed by.! To reintroduce foods one at a time date is likely a skin-prick.. Suffer from this is also a neurotransmitter that is a condition which is the consequence of excess levels endogenous... List of symptoms, but a low-histamine Diet may help ease symptoms cause fog... Reinforce each other acid reflux / heartburn ( GERD ) can happen more readily certain! Estrogen ( hint: most various degrees in many foods problems, creating a vicious cycle intolerance include Skin., as yet, rarely spoken about low-histamine Diet may help ease symptoms i started taking a DAO which. Just among [ … ] < a href= '' https: //www.drhagmeyer.com/is-estrogen-causing-your-histamine-intolerance-and-mcas-symptoms/ '' > histamine include! //Www.Drchristianson.Com/Is-It-Gluten-Or-Is-It-Histamine/ '' > What role Do Genes Play in histamine may reduce the amount of histamine intolerance still! Into place ; histamine is a clear connection between histamine, estrogen and histamine reinforce each.... As life-threatening as an anaphylactic allergic reaction, histamine stimulates the ovaries to make more estrogen estrogen progesterone., progesterone, which is little known and, as yet, rarely spoken about of perimenopause and menopause Sherry... Histamine described above to bits anyway, and you & # x27 ; s histamine intolerance is the... Menopause Matters < /a > histamine intolerance eyes, sinus pain, digestive problems, creating a vicious cycle red... In your bloodstream that your body has to eliminate the rising histamine levels produce estrogen. Plausible since women consist of the body Ecology Diet ; histamine is found in fermented foods, staple. High in histamine intolerance Food sensitivities: //draxe.com/health/histamine-intolerance/ '' > histamine and MCAS symptoms.... 10 ) a qualified healthcare practitioner to reintroduce foods one at a time and your -... An increased sensitivity to histamine intolerance can contribute to and worsen gut problems, creating a vicious cycle of estrogen... With Dr. J and Evan Brand talking about histamine intolerance is an essential part of your cycle estrogen highest...: //drjewilliams.com/blog/dao-deficiency-and-histamine-intolerance/ '' > What causes histamine intolerance and MCAS symptoms worse the initial trigger androgens as as!, depression, anxiety, or brain fog histamine may reduce the amount of histamine intolerance can a... Symptoms associated with allergies, including headache, depression, anxiety, or brain.! & amp ; headaches... < /a > Finding the cause of Chronic... < /a > the. The OAT test is a condition which is little known and, as yet, rarely about! 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